Myer’s Intravenous vitamin / mineral infusions
Myers’ Injection History
The Myers’ injection was pioneered by Dr John Myers, who used intravenous vitamins and minerals in his treatment regimes. A modified Myers regime was then developed by Dr Alan Gaby, MD, that typically included magnesium, calcium, thiamine, B12, B complex, vitamin C, which he found to frequently improve a wide variety of conditions such as asthma attacks, acute migraines, fatigue, fibromyalgia, acute muscle spasm, upper respiratory tract infections, chronic sinusitis, and seasonal allergic rhinitis (Gaby, A, Nutritional Medicine 2nd Ed).
Rationale for Myers’ / IV Nutrient Injections:
IV administration of nutrients can result in serum levels much higher than possible with oral administration (Okayama et al, JAMA 1987; Sydow M et al, Intensive Care Med. 1993.)
Magnesium may promote smooth muscle relaxation in blood vessels and bronchial muscle (Iseri LT et al. Am Heart J. 1984)(Brunner EH et al. J Asthma. 1985.), that may be beneficial for high blood pressure, bronchial asthma, migraine headache.
IV administration of 7.5 g of vitamin C over an hour has been demonstrated to reduce serum histamine levels by 31% (Hagel AF et al. Naunyn Schmiedebergs Arch Pharmacol. 2013.) This may be beneficial for allergic conditions.
Some nutrients may exert effects that are concentration dependent, such as anti-viral effects of vitamin C at 10-15 mg/dl (Harakeh S et al. Proc Natl Acad Sci. 1990.), only achieved through IV administration
Conditions that may be improved by Myers’ (IV vitamin/mineral) injections (personal experience as per Alan Gaby, MD; Gaby, A, Nutritional Medicine 2nd Ed.)
Fibromyalgia / polymyalgia rheumatica
Upper respiratory tract infection
Seasonal Allergic rhinitis
Modified Myers’ ingredients: Magnesium, sometimes calcium, Vitamin C, B-complex, B6, B5. Formulation may be altered to better meet patient case specifics. This may be diluted to ~35mL with sterile water and given as an IV push, or push into 100mL saline and given slower as an IV drip.
Myers’ injection safety:
Generally well tolerated by most patients in our experience. Dr Alan Gaby (MD) boasts that he had no adverse reactions in approximately 15,000 treatments when administered with caution and respect (Gaby, Alan. Nutritional Medicine, 2nd Ed.) Extra caution should be taken in potassium depleting conditions and medications (e.g. taken potassium depleting medications; states of low potassium: potassium depleting diuretics, beta agonists, glucocorticoids, diarrhea, vomiting, malnourishment), as IV magnesium can potentially worsen low blood potassium levels (can increase risk of digoxin induced cardiac arrhythmias). Conditions in which magnesium may be omitted include Myasthenia gravis, urinary tract infections with elevated urinary phosphates, hyperparathyroidism. Lower nutrient doses may be used in mild to moderate renal insufficiency. The Myers’ injection often causes a sensation of heat (from magnesium.) Low blood pressure and excessive heat may be associated with rapid injection, and higher dose of magnesium. Lower magnesium doses and slower injections (e.g. IV drip) may be indicated for those with lower blood pressure. Anaphylactic reactions to thiamine (B1) have been reported in the medical literature on the rare occasion. The Myers’ injection tends to be hypertonic (concentrated), thus tenderness, burning sensation at the injection site, vein irritation, phlebitis is possible. Often repositioning the needle in the vein or further diluting nutrients can help reduce or eliminate pain or irritation. Myers’ injection given as an IV drip (in 100cc of saline tends to be less hypertonic/concentrated).
Baseline bloodwork is run prior to any intravenous injection therapy, including by not limited to, kidney function (creatinine), liver enzymes, red/white blood cells, and other blood labs depending on the case. Thyroid hormone (blood TSH, T4, T3, reverse T3, TPO), adrenal (AM blood cortisol, 4 point salivary cortisol) and/or other lab testing may be recommended as per case history and physical exam findings, to better help elucidate attributing factors to chief concerns and presenting symptoms.
How Many Treatments Are Needed and How Often Are They Given?
The number and frequency of Myers’ and other types of intravenous vitamin/mineral injections depends on the condition being treated. For example, for fatigue, once or twice weekly injections may be recommended for 4-6 weeks, then as needed after that. Some patients may benefit in our experience to receive Myers’ injections during periods of acute stress (e.g. work/life stress, physical stress) to help get them through these rough patches in life (once or twice weekly), then as needed after that. Myers’ injections may take as little as 5-10 minutes for an ‘IV push’, to 20-30 minutes for the Myers’ drip (in 100 mL saline.) IVs with extra vitamin C typically take longer, depending on how much vitamin C is added, and the amount of fluid (vitamin C is hypertonic/quite concentrated, thus IVs are more voluminous with extra vitamin C).
Myers’ injections are billed at $55-60 (IV push, IV drip respectively). Larger doses of vitamin C may be used in conjunction with typical Myers’ vitamins/minerals, and typically billed according to the dose of Vitamin C ($80-150).
References: Myers’, Intravenous vitamin/mineral injections
Gaby AR. 2002. Intravenous nutrient therapy: the "Myers' cocktail". Altern Med Rev. 2002 Oct;7(5):389-403.
Ali A, Njike VY, Northrup V, Sabina AB, Williams AL, Liberti LS, Perlman AI, Adelson H, Katz DL. 2009. Intravenous micronutrient therapy (Myers' Cocktail) for fibromyalgia: a placebo-controlled pilot study. J Altern Complement Med. 2009 Mar;15(3):247-57.
Okayama H, Aikawa T, Okayama M, Sasaki H, Mue S, Takishima T. 1987. Bronchodilating effect of intravenous magnesium sulfate in bronchial asthma. JAMA. 1987 Feb 27;257(8):1076-8.
Rowe BH, Bretzlaff JA, Bourdon C, Bota GW, Camargo CA Jr. 2000. Magnesium sulfate for treating exacerbations of acute asthma in the emergency department. Cochrane Database Syst Rev. 2000;(2):CD001490.
Sydow M, Crozier TA, Zielmann S, Radke J, Burchardi H. 1993. High-dose intravenous magnesium sulfate in the management of life-threatening status asthmaticus. Intensive Care Med. 1993;19(8):467-71.
Harakeh S, Jariwalla RJ, Pauling L. 1990. Suppression of human immunodeficiency virus replication by ascorbate in chronically and acutely infected cells. Proc Natl Acad Sci U S A. 1990 Sep;87(18):7245-9.
Harakeh S1, Niedzwiecki A, Jariwalla RJ. 1994. Mechanistic aspects of ascorbate inhibition of human immunodeficiency virus. Chem Biol Interact. 1994 Jun;91(2-3):207-15.
Hagel AF, Layritz CM, Hagel WH, Hagel HJ, Hagel E, Dauth W, Kressel J, Regnet T, Rosenberg A, Neurath MF, Molderings GJ, Raithel M. 2013. Intravenous infusion of ascorbic acid decreases serum histamine concentrations in patients with allergic and non-allergic diseases. Naunyn Schmiedebergs Arch Pharmacol. 2013 Sep;386(9):789-93.
Iseri LT, French JH. 1984. Magnesium: nature's physiologic calcium blocker. Am Heart J. 1984 Jul;108(1):188-93.
Brunner EH, Delabroise AM, Haddad ZH. 1985. Effect of parenteral magnesium on pulmonary function, plasma cAMP, and histamine in bronchial asthma. J Asthma. 1985;22(1):3-11.
Sharma SK, Bhargava A, Pande JN. 1994. Effect of parenteral magnesium sulfate on pulmonary functions in bronchial asthma. J Asthma. 1994;31(2):109-15.